Andreasson ASI, Borthwick LA, Gillespie C, Jiwa K, Scott J, Henderson P, Mayes J, Romano R, Roman M, Ali S, Fildes JE, Marczin N, Dark JH, Fisher AJ. The role of interleukin-1β as a predictive biomarker and potential therapeutic target during clinical ex-vivo lung perfusion. J Heart Lung Transplant. 12 May 2017 PubMed 28551353
Andreasson ASI, Karamanou DM, Gillespie CS, Ozalp F, Butt T, Hill P, Jiwa K, Walden HR, Green NJ, Borthwick LA, Clark SC, Pauli H, Gould KF, Corris PA, Ali S, Dark JH, Fisher AJ. Profiling inflammation and tissue injury markers in perfusate and bronchoalveolar lavage fluid during human ex vivo lung perfusion. Eur J Cardiothorac Surg. 2017 PubMed 28082471
Barlow AD, Saeb-Parsy K, Watson CJE. An analysis of the survival outcomes of simultaneous pancreas and kidney transplantation compared to live donor kidney transplantation in patients with type 1 diabetes: a UK Transplant Registry study. Transpl Int 2017;30(9):884–892 PubMed 28319322
Beach TE, Prag HA, Pala L, Logan A, Huang MA, Gruszczyk AV, Martin JL, Mahbubani K, Hamed MO, Hosgood SA, Nicholson ML, James AM, Hartley RC, Murphy MP, Saeb-Parsy K. Targeting Succinate Dehydrogenase with Malonate Ester Pro-Drugs Decreases Renal Ischemia Reperfusion Injury. Redox Biol 2020 Sep;36:101640 PubMed 32863205
Burman A, Watson CJE, Kosmoliaptsis V. Ethylene glycol poisoning should not contraindicate liver donation. Transplantation Direct 2017 Sep 8;3(10):e212 PubMed 29026875
Collett D, Friend PJ, Watson CJE. Factors associated With Short- and Long-Term Liver Graft Survival in the United Kingdom: Development of a UK Donor Liver Index. Transplantation. 2016 Dec 1 PubMed 27906826
Copley HC, Elango M, Kosmoliaptsis V. Assessment of human leukocyte antigen immunogenicity: current methods, challenges and opportunities. Curr Opin Organ Transplant 2018 Jun 4 PubMed 29870434
DiRito JR, Hosgood SA, Tietjen GT, Nicholson ML. The future of marginal kidney repair in the context of normothermic machine perfusion. Am J Transplant. 2018 Jun 7 PubMed 29878499
DiRito JR, Hosgood SA, Reschke M, Albert C, Bracaglia LG, Ferdinand JR, Stewart BJ, Edwards CM, Vaish AG, Thiru S, Mulligan DC, Haakinson DJ, Clatworthy MR, Saltzman WM, Pober JS, Nicholson ML, Tietjen GT. Lysis of cold-storage-induced microvascular obstructions for ex vivo revitalization of marginal human kidneys. Am J Transplant. 2020 Jul 5 PubMed 32627324
Dyson NJ, Kattner N, Honkanen-Scott M, Hunter B, Doyle JA, White K, Davey TS, Ploeg R, Bury YA, Tiniakos DG, Shaw JAM, Scott WE. Development and application of a semi-quantitative scoring method for ultrastructural assessment of acute stress in pancreatic islets. Transplant Direct. 2021 Dec 16 PubMed 34934809
Elliott TR, Nicholson ML, Hosgood SA. Normothermic kidney perfusion: an overview of protocols and strategies. Am J Transplant. 2020 Sep 8 PubMed 32897651
Ferdinand JR, Hosgood SA, Moore T, Ward CJ, Castro-Dopico T, Nicholson ML, Clatworthy MR. Cytokine absorption during human kidney perfusion reduces delayed graft function-associated inflammatory gene signature. Am J Transplant. 2020 Oct 23 PubMed 33098231
Ferdinand JR, Morrison MI, Andreasson A, Charlton C, Chhatwal AK, Scott WE 3rd, Borthwick LA, Clatworthy MR, Fisher AJ. Transcriptional analysis identifies potential novel biomarkers associated with successful ex-vivo perfusion of human donor lungs. Clin Transplant. 2021 Dec 26:e14570 PubMed 34954872
Fisher AJ, Dark JH. Ex vivo repair of human donor lungs for transplantation. Nat Med. 2020 Jul 10 PubMed 32651577
Gilmour J, Griffiths C, Pither T, Scott WE, Fisher AJ. Normothermic machine perfusion of donor-lungs ex-vivo: promoting clinical adoption. Curr Opin Organ Transplant. 2020 Apr 16 PubMed 32304426
Griffiths C, Scott WE, Ali S, Fisher AJ. Maximising organs for donation: the potential for ex-situ normothermic machine perfusion. QJM. 2020 Jan 14 PubMed 31943119
Hakeem A, Chen J, Iype S, Clatworthy M, Watson C, Godfrey EM, Upponi S, Saeb-Parsy K. Pancreatic allograft thrombosis: Suggestion for a CT grading system and management algorithm. Am J Transplant. 2017 Jul 18 PubMed 28719059
Hamed M, Logan A, Gruszczyk AV, Beach TE, James AM, Dare AJ, Barlow A, Martin J, Georgakopoulos N, Gane AM, Crick K, Fouto D, Fear C, Thiru S, Dolezalova N, Ferdinand JR, Clatworthy MR, Hosgood SA, Nicholson ML, Murphy MP, Saeb-Parsy K. Mitochondria-targeted antioxidant MitoQ ameliorates ischaemia-reperfusion injury in kidney transplantation models. Br J Surg. 2021 May 8:znab108 PubMed 33963377
Harper IG, Ali JM, Harper SJ, Wlodek E, Alsughayyir J, Negus MC, Qureshi MS, Motalleb-Zadeh R, Saeb-Parsy K, Bolton EM, Bradley JA, Clatworthy MR, Conlon TM, Pettigrew GJ. Augmentation of recipient adaptive alloimmunity by donor passenger lymphocytes within the transplant. Cell Rep. 2016 May 10; 15(6): 1214–1227 PubMed 27134179
Hosgood SA, Nicholson ML. An Assessment of Urinary Biomarkers in a Series of Declined Human Kidneys Measured During ex-vivo Normothermic Kidney Perfusion. Transplantation. 2016 Sep 27 PubMed 27681269
Hosgood SA, Saeb-Parsy K, Hamed MO, Nicholson ML. Successful Transplantation of Human Kidneys Deemed Untransplantable but Resuscitated by Ex Vivo Normothermic Machine Perfusion. Am J Transplant. 2016 Nov; 16(11): 3282–3285 PubMed 27273794
Hosgood SA, Saeb-Parsy K, Wilson C, Callaghan C, Collett D, Nicholson ML. Protocol of a randomised controlled, open-label trial of ex vivo normothermic perfusion versus static cold storage in donation after circulatory death renal transplantation. BMJ Open 2017 Jan 23;7(1):e012237 PubMed 28115329
Hosgood SA, Thompson E, Moore TA, Wilson CH, Nicholson ML. Normothermic machine perfusion for the assessment and transplantation of declined human kidneys from donation after circulatory death donors. Br J Surg. 2017 Dec 6. PubMed 29210064
Hosgood SA, Nicholson ML. The evolution of donation after circulatory death donor kidney repair in the United Kingdom. Curr Opin Organ Transplant. 2018 Feb; 23(1):130–135 PubMed 29045248
Hosgood SA, Hoff M, Nicholson ML. Treatment of transplant kidneys during machine perfusion. Transpl Int. 2020 Sept 24 PubMed 32970886
Hosgood SA, Nicholson ML. A short period of normothermic machine perfusion may not be able to predict primary nonfunction in uncontrolled circulatory death kidneys. Transplantation 2021 Jan 1;105(1):e11-e12 PubMed 33350632
Hosgood SA, Brown RJ, Nicholson ML. Advances in kidney preservation techniques and their application in clinical practice. Transplantation. 2021 Mar 18 PubMed 33982904
Jiang W, Johnson C, Simecek N, López-Álvarez MR, Di D, Trowsdale J, Traherne JA. qKAT: a high-throughput qPCR method for KIR gene copy number and haplotype determination. Genome Med. 2016 Sep 29; 8(1): 99 PubMed 27686127
Jochmans I, Nicholson ML, Hosgood SA. Kidney perfusion: some like it hot others prefer to keep it cool. Curr Opin Organ Transplant. 2017 Mar 15 PubMed 28301386
Jordan NP, Nicholson ML, Hosgood SA. MicroRNA-126-3p is downregulated in human kidneys in a model of reperfusion injury. Kidney Int Rep 2020 Sep 24;5(12):2357-2360 PubMed 33305131
Kattner N, Dyson N, Bury Y, Tiniakos D, White K, Davey T, Eliasson L, Tindale L, Wagner B, Honkanen-Scott M, Doyle J, Ploeg R, Shaw JAM, Scott WE III. Development and validation of a quantitative electron microscopy score to assess acute cellular stress in the human exocrine pancreas. J Pathol Clin Res. 2020 Nov 22 PubMed 33225596
Khushnood A, Butt TA, Jungschleger J, Henderson P, Smith JH, De Rita F, Nassar M, Page A, Messer S, Large S, Dark JH, Parry G, Reinhardt Z, Hasan A. Paediatric donation after circulatory determined death heart transplantation using donor normothermic regional perfusion and ex situ heart perfusion: a case report. Pediatr Transplant. 2019 Jul 4 PubMed 31273913
Kosmoliaptsis V, Mallon DH, Chen Y, Bolton EM, Bradley JA, Taylor CJ. Alloantibody Responses After Renal Transplant Failure Can Be Better Predicted by Donor–Recipient HLA Amino Acid Sequence and Physicochemical Disparities Than Conventional HLA Matching. Am J Transplant. 2016 Jul; 16(7): 2139–47 PubMed 26755448
MacGowan GA, Dark JH, Corris PA, Nair AR. Effects of drug abuse, smoking and alcohol on donor hearts and lungs. Transpl Int 2019 Jun 6 PubMed 31172575
Mah T-J, Mallon DH, Brewster O, Saeb-Parsy K, Butler AJ, Bradley JA, Kosmoliaptsis V. Ureteric complications in recipients of kidneys from donation after circulatory death donors. Clinical Transplantation. 2017 Jan 23 PubMed 28111805
Mallon DH, Kling C, Robb M, Ellinghaus E, Bradley JA, Taylor CJ, Kabelitz D, Kosmoliaptsis V. Predicting humoral alloimmunity from differences in donor-recipient HLA surface electrostatic potential. J Immunol 2018 Dec 15; 201(12): 3780–3792 PubMed 30429288
Manara A, Shemie SD, Large S, Healey A, Baker A, Badiwala M, Berman M, Butler, AJ, Chaudhury P, Dark J, Forsythe J, Freed DH, Gardiner D, Harvey D, Hornby L, MacLean J, Messer S, Oniscu GC, Simpson C, Teitelbaum J, Torrance S, Wilson LC, Watson CJE. Maintaining the permanence principle for death during in situ normothermic regional perfusion for donation after circulatory death organ recovery: A United Kingdom and Canadian proposal. Am J Transplant. 2020 Jan 10 PubMed 31922653
Martin J, Gruszczyk A, Beach T, Murphy M and Saeb-Parsy K. Mitochondrial mechanisms and therapeutics in ischaemia reperfusion injury. Paediatr Nephrol 2018 2 Jun PubMed 29860579
Martin JL, Costa ASH, Gruszczyk AV, Beach TE, Allen FM, Prag HA, Hinchy EC, Mahbubani K, Hamed M, Tronci L, Nikitopoulou E, James AM, Krieg T, Robinson AJ, Huang MM, Caldwell ST, Logan A, Pala L, Hartley RC, Frezza C, Saeb-Parsy K, Murphy MP. Succinate accumulation drives ischaemia-reperfusion injury during organ transplantation. PubMed 32395697
Mirshekar-Syahkal B, Summers D, Bradbury LL, Aly M, Bardsley V, Berry M, Norris JM, Torpey N, Clatworthy MR, Bradley JA, Pettigrew GJ. Local expansion in circulatory death kidney transplant activity improves wait-listed outcomes and addresses inequities of access to transplantation. Am J Transplant. 2016 Jul 18 PubMed 27428662
Morrison M, Pither T and Fisher A. Pathophysiology and classification of primary graft dysfunction after lung transplantation. J Thorac Dis. 2017, 9(10), 4084–4097 PubMed 29268419
Owen RV, Thompson ER, Tingle SJ, Ibrahim IK, Manas DM, White SA, Wilson CH. Too Fat for Transplant? The Impact of Recipient BMI on Pancreas Transplant Outcomes. Transplantation. 2021 Apr 1;105(4):905-915 PubMed 33741849
Richards JA, Randle LV, Butler MChir AJ, Martin JL, Fedotovs A, Davies SE, Watson CJE, Robertson PA. Pilot study of a noninvasive real-time optical backscatter probe in liver transplantation. Transpl Int. 2021 Apr;34(4):709-720 PubMed 33462839
Saeb-Parsy K, Martin JL, Summers DM, Watson CJE, Krieg T, Murphy MP. Mitochondria as Therapeutic Targets in Transplantation. Trends Mol Med. 2021 Feb;27(2):185–198 PubMed 32952044
Smith SF, Hosgood SA, Nicholson ML. Ischemia-reperfusion injury in renal transplantation: 3 key signalling pathways in tubular epithelial cells. Kidney Int 01 Jan 2019, 95(1): 50–56 PubMed 30606429
Smith TB, Nicholson MLN, Hosgood SA. Advances in hypothermic and normothermic perfusion in kidney transplantation. Transplantology 2021; 2(4): 460–477 Full article
Surianarayanan V, Hoather TJ, Tingle SJ, Thompson ER, Hanley J, Wilson CH. Interventions for preventing thrombosis in solid organ transplant recipients. Cochrane Database Syst Rev. 2021 Mar 15;3(3):CD011557 PubMed 33720396
Taylor CJ, Kosmoliaptsis V, Martin J, Knighton G, Mallon D, Bradley JA, Peacock S. Technical Limitations of the C1q single-antigen bead assay to detect complement binding HLA-specific antibodies. Transplantation. 2016 Jul 1 PubMed 27306532
Thompson ER, Hosgood SA, Nicholson ML, Wilson CH. Early versus late ureteric stent removal after kidney transplantation. Cochrane Database Syst Rev. 2018 Jan 29 PubMed 29376218
Thompson ER, Irwin EA, Trotter P, Ibrahim IK, Tingle SJ, White SA, Manas DM, Wilson CH. UK registry analysis of donor substance misuse and outcomes following pancreas transplantation. Clin Transplant 2019 Feb 12 PubMed 30659654
Thompson ER, Bates L, Ibrahim IK, Sewpaul A, Stenberg B, McNeill A, Figueiredo R, Girdlestone T, Wilkins GC, Wang L, Tingle SJ, Scott WE 3rd, de Paula Lemos H, Mellor AL, Roobrouck VD, Ting AE, Hosgood SA, Nicholson ML, Fisher AJ, Ali S, Sheerin NS, Wilson CH. Novel delivery of cellular therapy to reduce ischemia reperfusion injury in kidney transplantation. Am J Transplant. 2020 Jun 7 PubMed 32506663
Thompson ER, Connelly C, Ali S, Sheerin NS, Wilson CH. Cell therapy during machine perfusion. Transpl Int. 2021 Jan;34(1):49-58 Epub 2020 Nov 24 PubMed 33131097
Tietjen GT, Hosgood SA, DiRito J, Cui J, Deep D, Song E, Kraehling JR, Piotrowski-Daspit AS, Kirkiles-Smith NC, Al-Lamki R, Thiru S, Bradley JA, Saeb-Parsy K, Bradley JR, Nicholson ML, Saltzman WM, Pober JS. Nanoparticle targeting to the endothelium during normothermic machine perfusion of human kidneys. Sci Transl Med. 2017 29 Nov; 9(418), eaam6764 PubMed 29187644
Tingle SJ, Figueiredo RS, Moir JAG, Goodfellow M, Talbot D, Wilson CH. Machine perfusion preservation versus static cold storage for deceased donor kidney transplantation. Cochrane Database of Systematic Reviews. 2019 Mar 15;3:CD011671 PubMed 30875082
Tingle SJ, Sewpaul A, Bates L, Thompson ER, Shuttleworth V, Figueiredo R, Ibrahim IK, Ali S, Wilson C, Sheerin NS. Dual microRNA blockade increases expression of antioxidant protective proteins: implications for ischaemia reperfusion injury. Transplantation. 2020 Mar 2 PubMed 32150044
Tingle SJ, Thompson ER, Ali SS, Figueiredo R, Hudson M, Sen G, White SA, Manas DM, Wilson CH. Risk factors and impact of early anastomotic biliary complications after liver transplantation: UK registry analysis. BJS Open. 2021 Mar 5;5(2):zrab019 PubMed 33855363
Tingle SJ, Thompson ER, Bates L, Ibrahim IK, Figueiredo R, Bury Y, Wilson CH. Microvascular obstructions in portal bile duct capillaries and hepatic sinusoids during normothermic machine perfusion of marginal human livers. Am J Transplant. 2021 Apr;21(4):1662-1664 PubMed 33037747
Trotter PB, Robb M, Hulme W, Summers D, Watson CJE, Bradley JA, Neuberger J. Transplantation of organs from deceased donors with meningitis and encephalitis: a UK registry analysis. Transplant Infectious Disease 2016 Oct 4 PubMed 27699935
Trotter PB, Robb M, Summers D, Watson CJE, Clatworthy M, Bradley JA, Hill QA, Neuberger J. Donors With Immune Thrombocytopaenia: Do They Pose a Risk to Transplant Recipients? Am J Transplant. 2016 Nov 7 PubMed 27935215
Trotter PB, Summers DM, Robb M, Hulme W Ushiro-Lumb I, Watson CJE, Neuberger J, Bradley JA. Deceased organ donors with a history of increased risk behavior for the transmission of blood-borne viral infection: the UK experience. Transplantation 2017 Jul;101(7):1679-1689 PubMed 28291157
Trotter PB, Summers DM, Ushiro-Lumb I, Robb M, Bradley JA, Powell J, Watson CJE, Neuberger J. Use of organs from hepatitis C virus positive donors for uninfected recipients: a potential cost-effective approach to save lives? Transplantation 2017 Nov 22 PubMed 29166338
Trotter PB, Jochmans I, Hulme W, Robb M, Watson C, Neuberger J, Bradley JA. Transplantation of kidneys from DCD and DBD donors who died after ligature asphyxiation: the UK experience. Am J Transplant. 2018 Jun 27 PubMed 29947090
Wang L, Wang T, Rushton SN, Parry G, Dark JH, Sheerin NS. The Impact of Severe Acute Kidney Injury Requiring Renal Replacement Therapy on Survival and Renal Function of Heart Transplant Recipients – A UK Cohort Study. Transpl Int 2020 Jun 16 PubMed 32542834
Wang L, Thompson E, Bates L, Pither T, Hosgood SA, Nicholson ML, Watson CJE, Wilson C, Fisher AJ, Ali S, Dark JH. Flavin mononucleotide as a biomarker of organ quality – a pilot study. Transplant Direct. 2020 Aug 21;6(9):e600 PubMed 32904032
Wang L, MacGowan GA, Ali S, Dark JH. Ex situ heart perfusion: the past, present and future. J Heart Lung Transpl 2020 Oct 14 PubMed 33162304
Watson CJ, Kosmoliaptsis V, Randle LV, Gimson AE, Brais R, Klinck JR, Hamed M, Tsyben A, Butler AJ. Normothermic perfusion in the assessment and preservation of declined livers prior to transplantation: hyperoxia and vasoplegia – important lessons from the first 12 cases. Transplantation 2017 Jan 25 PubMed 28437389
Watson CJE, Kosmoliaptsis V, Pley C, Randle L, Fear C, Crick K, Gimson AE, Allison M, Upponi S, Brais R, Jochmans I, Butler AJ. Observations on the ex situ perfusion of livers for transplantation. Am J Transplant. 2018 Feb 8 PubMed 29419931
Watson CJE, Jochmans I. From “Gut Feeling” to Objectivity: Machine Preservation of the Liver as a Tool to Assess Organ Viability. Current Transplantation Reports 2018;5(1):72–81 PubMed 29564205
Watson CJE, Hunt F, Messer S, Currie I, Large S, Sutherland A, Crick K, Wigmore SJ, Fear C, Cornateanu S, Randle LV, Terrace JD, Upponi S, Taylor R, Allen E, Butler AJ, Oniscu GC. In situ normothermic perfusion of livers in controlled circulatory death donation may prevent ischemic cholangiopathy and improve graft survival. Am J Transplant 2018 Dec 27 PubMed 30589499
Watson CJE, Johnson RJ, Mumford L. Overview of the evolution of the UK kidney allocation schemes. Curr Transplant Rep 2020 Mar 12 Full article
Wiebe C, Kosmoliaptsis V, Pochinco D, Taylor C, Nickerson P. A comparison of HLA molecular mismatch methods to determine HLA immunogenicity. Transplantation 2018 Feb 13 PubMed 29443827
Wiebe C, Kosmoliaptsis V, Pochinco D, Gibson IW, Ho J, Birk PE, Goldberg A, Karpinski M, Shaw J, Rush DN, Nickerson PW. HLA-DR/DQ molecular mismatch: a prognostic biomarker for primary alloimmunity. Am J Transplant 2018 Nov 10 PubMed 30414349